VISDB Viral Integration Site DataBase

VIS ID

TVIS10012300

Fusion event

HBV-ST6GAL1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

454

Orient

-

Integrated sequence

CCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACT| |ATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTAT

Chromosome

chr3

Cytoband

q27.3

Reference genome

Start

End

186667307/186949519 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-492 ; hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-18a-3p ; hsa-mir-218-5p ; hsa-mir-8081 ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-526b-5p ; hsa-mir-924 ; hsa-mir-5009-3p

Nearest miRNA

hsa-let-7g/Upstream/162742; hsa-mir-28/Downstream/1739262;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/18205, chr3-CpG: 63/Downstream/189620

Upstream sequence

tgttgcagactgcctgcctgagggtagaagacatgccccaacatgcacacacagcccgtaggcaaacacttaataaacttaaaggcatttattagtctct

Downstream sequence

GGGGAAAAAACTGGCCAGGAGGAGATGAACCAAAGGCGTCTCACAGGGAATCCTTCTGTACTTGAAGAGTCCTGCCCTTGTCTCCCCAGCCAGATCCAGT