VISDB Viral Integration Site DataBase

VIS ID

TVIS10012301

Fusion event

HBV-ST6GAL1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1639

Orient

-

Integrated sequence

ACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATA| |TTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGG

Chromosome

chr3

Cytoband

q27.3

Reference genome

Start

End

186667337/186949549 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-492 ; hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-18a-3p ; hsa-mir-218-5p ; hsa-mir-8081 ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-526b-5p ; hsa-mir-924 ; hsa-mir-5009-3p

Nearest miRNA

hsa-let-7g/Upstream/162772; hsa-mir-28/Downstream/1739232;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/18235, chr3-CpG: 63/Downstream/189590

Upstream sequence

tgtatgtctgtattcttcaagatgtacaacatttagaatactgccatatatgaacagacatcattttacttcttcctttccaaaaattttctgctcagac

Downstream sequence

CAAAGGCGTCTCACAGGGAATCCTTCTGTACTTGAAGAGTCCTGCCCTTGTCTCCCCAGCCAGATCCAGTGACTCACAGTAGGAGGGCTTGGAGGCAACT