Basic Information
VIS ID
TVIS10012306
Fusion event
HBV-C3orf84 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1821
Orient
+
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
End
49218177/49180744 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12127/Upstream/80830; hsa-let-7g/Downstream/93376;
Upstream sequence
atttttgtttgcaatgagtacacgcaaatgatactaaagcagtggtccagtcatactttgaaaaATGTTGATGAGTTTCAGGAGAGTGGTTAGGACTTTT
Downstream sequence
atggtgaaaccccgtctctactaaaaatacaaaaaatgtgctgggtgtgatggcgggcgcctgtagtcccagctactcgggaggttgaggcaggagaatg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate