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VISDB
Viral Integration Site DataBase
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TVIS10012307
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012307
Fusion event
HBV-ATXN7 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1750
Orient
-
Integrated sequence
CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAG| |GAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTG
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
63874236/63888560 (Hg38)
End
63874236/63888560 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATXN7
miRNAs that regulate target gene
hsa-mir-192-5p
;
hsa-mir-423-3p
;
hsa-mir-342-3p
;
hsa-mir-92a-3p
;
hsa-mir-17-5p
;
hsa-mir-3978
;
hsa-mir-4753-3p
;
hsa-mir-452-3p
;
hsa-mir-5093
;
hsa-mir-9-5p
;
hsa-mir-130b-5p
;
hsa-mir-4635
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-6873-3p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-502-5p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-3124-3p
;
hsa-mir-6845-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-5695
;
hsa-mir-519d-5p
;
hsa-mir-6832-3p
;
hsa-mir-4262
;
hsa-mir-181d-5p
;
hsa-mir-181c-5p
;
hsa-mir-181b-5p
;
hsa-mir-181a-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
Nearest miRNA
hsa-let-7g/Upstream/3270690; hsa-mir-12124/Downstream/3336904;
Nearest TSS
ENST00000440867/Upstream/24000;
ENST00000475897/Downstream/9839;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/23879
,
chr3-CpG: 136/Downstream/23156
Upstream sequence
aatttgtgagaaaaaatagagtacagaaaagtaatttaaaacagttttgaggaatataaaacaaaggaaaaatggtagcttttaccacaacaatcagtaa
Downstream sequence
gaggtcaagagatcgagaccatcctggccaacatggtgaaaccctgtctctactaaaaatacaaaaatagctgggggtggtgtcaagtgcctataatccc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Sample Information
×
Sample name
791P
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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