VISDB Viral Integration Site DataBase

VIS ID

TVIS10012308

Fusion event

HBV-ATXN7 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1956

Orient

+

Integrated sequence

TCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTT| |TTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACC

Chromosome

chr3

Cytoband

p14.1

Reference genome

Start

End

63874324/63888648 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-423-3p ; hsa-mir-342-3p ; hsa-mir-92a-3p ; hsa-mir-17-5p ; hsa-mir-3978 ; hsa-mir-4753-3p ; hsa-mir-452-3p ; hsa-mir-5093 ; hsa-mir-9-5p ; hsa-mir-130b-5p ; hsa-mir-4635 ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-502-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-3124-3p ; hsa-mir-6845-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-6832-3p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p

Nearest miRNA

hsa-let-7g/Upstream/3270778; hsa-mir-12124/Downstream/3336816;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/23967, chr3-CpG: 136/Downstream/23068

Upstream sequence

tgaggtgggcagatggcttgagcctaagagttcgagaccagcctgggtagcatagcaagaccttgtctctacaaaaaaatacaaagattagcagggcatg

Downstream sequence

gcctataatcccagttactcgggaggctgaggcaggagaatcgcttgaacctgggaggcagaggttgcagtgagtcgagatcgtgccagtgcactccagc