Basic Information
VIS ID
TVIS10012309
Fusion event
HBV-LINC01266 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1758
Orient
-
Integrated sequence
AGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAG| |GTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTC
Host Sequence
Chromosome
chr3
Cytoband
p26.3
Reference genome
GRCh37/hg19
Start
783656/741972 (Hg38)
End
783656/741972 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC01266
Nearest miRNA
hsa-let-7g/Downstream/4508205;
Nearest TSS
ENST00000440867/Upstream/205719; ENST00000423193/Downstream/115152;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/432762, chr3-CpG: 182/Downstream/1356373
Nearby gene
CHL1(-332559) ; CNTN6(+350973) ;
Upstream sequence
GCCATCTGCGACATCACAACAGGGCTTTAGGGTAGAAGATAGATAGCAGTTCTGTGGATACAAGATCCCTATATAAGTTCTCTCACATTGGATACCATAT
Downstream sequence
tgtagaatgtgatgacatgagctacaaaagggcatttgtagggagctgcaagaaatcatggcctgaaaggagcattgaaaagcaaagagactatattcca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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