VISDB Viral Integration Site DataBase

VIS ID

TVIS10012313

Fusion event

HBV-RAB33B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1801

Orient

-

Integrated sequence

GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG

Chromosome

chr4

Cytoband

q31.1

Reference genome

Start

End

140396225/139475071 (Hg38)

Orient

+

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-100-5p ; hsa-mir-582-5p ; hsa-mir-6504-3p ; hsa-mir-633 ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-101-3p ; hsa-mir-5583-5p ; hsa-mir-3129-3p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-4459 ; hsa-mir-6516-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-455-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-4252 ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6087 ; hsa-mir-4537 ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-6786-3p ; hsa-mir-3192-5p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-7851-3p ; hsa-mir-490-3p

Nearest miRNA

hsa-mir-12113/Upstream/13967764; hsa-mir-1305/Downstream/3868389;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/20533, chr4-CpG: 212/Downstream/80156

Upstream sequence

TGGTGAAGGCACCACTCCAAAGAGTGTAGATACATACTGACCACAACAGAGACAGAATGTGTGTGTGTGCACACGTACACATGAACGAAAGAGGCTAGGG

Downstream sequence

CTCAAATTGGCTTTATTTGCATTTAGGGAGATCATGTTTTCTTAATCATGCTGGAATTTAAAAATTGTTTTACTTGTATCGAAATTAACCTTGATTTATA