VISDB Viral Integration Site DataBase

VIS ID

TVIS10012332

Fusion event

HBV-AHRR integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1666

Orient

+

Integrated sequence

ATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACT| |CTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGG

Chromosome

chr5

Cytoband

p15.33

Reference genome

Start

End

402278/402163 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-26a-5p ; hsa-mir-18a-5p ; hsa-mir-125b-5p

Nearest miRNA

hsa-mir-10397/Downstream/660733;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/9641, chr5-CpG: 51/Downstream/18946

Nearest cancer related gene

AHRR(TSG, No orient, 0)

Upstream sequence

tctggccccagccatctctccagcctcatttctgGTGACTCCCAGATCTGGCCCCAGCCATGTCTCTAGACTCCAAACTTATTCCTTATAATGCTCCCAC

Downstream sequence

acacaaaatggccagtttgtaggtggaaaggtgctcggcatcgccaggcacagggaagtgcaaatggaaaccgtcagcgagctcctctcacaccatcagg