Basic Information
VIS ID
TVIS10012349
Fusion event
HBV-chr6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
894
Orient
-
Integrated sequence
ACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTG| |GATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCA
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
82967902/82258185 (Hg38)
End
82967902/82258185 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/3718876; hsa-mir-1202/Downstream/8054557;
Nearest TSS
ENST00000381078/Upstream/10431; ENST00000535040/Downstream/105021;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/10060, chr6-CpG: 174/Downstream/105514
Nearby gene
IBTK(-10454) ; TPBG(+105021) ;
Upstream sequence
tttggaataggtgtggtgtggtgctgaaaaaaatgtatattctgttgatttggggtggagagctctgtagatgtcaattaggtctgcttggtgcagagct
Downstream sequence
ggcgtggtggcacacacctgtagtcgcagctacttgggaagctgagtcaggagaatcacttgaacccaggatgtggaggttgcagtgagccaagatcatg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate