VISDB Viral Integration Site DataBase

VIS ID

TVIS10012350

Fusion event

HBV-VPS41 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1852

Orient

+

Integrated sequence

GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT| |CATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTC

Chromosome

chr7

Cytoband

p14.1

Reference genome

Start

End

38902573/38862973 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-148a-3p ; hsa-let-7b-5p ; hsa-mir-197-3p ; hsa-mir-4634 ; hsa-mir-4695-3p ; hsa-mir-6787-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6736-3p ; hsa-mir-4714-3p ; hsa-mir-652-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p

Nearest miRNA

hsa-mir-1183/Upstream/1943541; hsa-mir-10399/Downstream/4287922;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/231412, chr7-CpG: 36/Downstream/112970

Upstream sequence

ctcagagtgcttctgtctagtttttatgtgaagatatttcctttttcaacatagttctgaaaccactcaaaaatatccctctgcaaattccacaaaaagg

Downstream sequence

AGAATGATTCAGAAACTCCCCCTAATTTATGGCAAATGTGTAAATCAGTGCTATCGCTTAAGCTGCACACATACACAAACAACAAATTATTTTTTCGAAT