VISDB Viral Integration Site DataBase

VIS ID

TVIS10012351

Fusion event

HBV-VPS41 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1513

Orient

-

Integrated sequence

GGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCG| |ACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGG

Chromosome

chr7

Cytoband

p14.1

Reference genome

Start

End

38902599/38862999 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-148a-3p ; hsa-let-7b-5p ; hsa-mir-197-3p ; hsa-mir-4634 ; hsa-mir-4695-3p ; hsa-mir-6787-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6736-3p ; hsa-mir-4714-3p ; hsa-mir-652-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p

Nearest miRNA

hsa-mir-1183/Upstream/1943567; hsa-mir-10399/Downstream/4287896;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/231438, chr7-CpG: 36/Downstream/112944

Upstream sequence

TAAGTTACACTAATAGAACTGTATCtggcattgttgtgaattgatagatgaatttggaaagaatttgtctttatgatactaaatcctttttatccaagaa

Downstream sequence

TTATGGCAAATGTGTAAATCAGTGCTATCGCTTAAGCTGCACACATACACAAACAACAAATTATTTTTTCGAATGGAAAATCCATGCCATATTGAGAGAC