Basic Information
VIS ID
TVIS10012364
Fusion event
HBV-LOC102724027 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1752
Orient
-
Integrated sequence
TACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGA| |GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT
Host Sequence
Chromosome
chr9
Cytoband
p23
Reference genome
GRCh37/hg19
Start
11185431/11185431 (Hg38)
End
11185431/11185431 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC102724027
Nearest miRNA
hsa-mir-101-2/Upstream/5177527; hsa-let-7a-1/Downstream/7387875;
Nearest TSS
ENST00000422679/Upstream/236950; ENST00000473763/Downstream/90883;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/572098, chr9-CpG: 37/Downstream/432833
Nearby gene
PTPRD(-572708) ; TYRP1(+1507955) ;
Upstream sequence
atgacacaggcagaaaactagaggaatgtggtgtcgccaaagcaagtgaagattgtttactaaggtaagagggaatgatcaactacgttaatggtacctg
Downstream sequence
ttttgtttctagcttattatacctaacatgtcttcctgttctttccaggttgctgaaatggcaagacttgattcttttttatagtgaatagcatcccatt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate