VISDB Viral Integration Site DataBase

VIS ID

TVIS10012366

Fusion event

HBV-ARHGAP6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1906

Orient

+

Integrated sequence

ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG| |ACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTC

Chromosome

chrX

Cytoband

p22.2

Reference genome

Start

End

11158631/11140511 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-5088-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p

Nearest miRNA

hsa-mir-3690-1/Upstream/3013450; hsa-let-7f-2/Downstream/178103;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/1067, chrX-CpG: 62/Downstream/286896

Upstream sequence

gttgagtggttttgagtgagtttcttatttctgaattctagtttgattgcactgtggtctgagagacagtttgttataatttctgatcttttacatttgc

Downstream sequence

AAGACTCTCTAGGCTCTGAAACTCTtggaagactcccggggctctgaggatggtggagccactggatatgtggagcctaggctgggccccttagtgacta