Basic Information
VIS ID
TVIS10012370
Fusion event
HBV-chrY integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2167
Orient
-
Integrated sequence
AGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATG| |TCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTT
Host Sequence
Chromosome
chrY
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
13808735/11688029 (Hg38)
End
13808735/11688029 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/7081801; hsa-mir-12120/Downstream/1791148;
Nearest TSS
ENST00000430575/Upstream/1777231; ENST00000417071/Downstream/974305;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/257597, chrY-CpG: 40/Downstream/101308
Nearby gene
GYG2P1(+709180) ;
Upstream sequence
tcttgggccaataaactagtttatgggactaaatgctttggcctcacacacatagagcattgtgacatgaaagtgaaacctgaaccaaggtgatgtaact
Downstream sequence
aatgcaatggaatggaatggaatggaatggaatggaatggaatgcaatggaatggaacatagaggactcatgtggaatagaacagaatggaatggaatcg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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