Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012375
Fusion event
HBV-COL25A1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1827
Orient
-
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
End
110168178/109247022 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/7916608; hsa-mir-1243/Downstream/241676;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/483816, chr4-CpG: 98/Downstream/54792
Upstream sequence
atatctacccaaagggaaataagtcattacatcaaaaagacacctacatgcatctgtttattgcagcacaatttcaaagatatggaaccaatctaagtac
Downstream sequence
TTAAAGTGTTCCAGATCAGCTGGAACATAGAAAAAGGAAGTAAAGAAAGATAAGCTTGAggctgggtgtggtggttcatgcctgtaatcccagcactttg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.