Basic Information
VIS ID
TVIS10012383
Fusion event
HBV-chr5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
722
Orient
-
Integrated sequence
GGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCAC| |TGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTT
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
End
11561/11561 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Downstream/1051335;
Nearest CpG islands
None/Target, None/Upstream, chr5-CpG: 87/Downstream/39129
Nearby gene
PLEKHG4B(+128812) ;
Upstream sequence
TGGCTGTTAGCTCACACCCATCTTCCTAGTCCTCATGTGTACATACACATTGGCCCAAAGGCAGTCTATAAAGACACAATGGTACTGCGCCTGTCTGCAT
Downstream sequence
aaccctaaccctaaccctaaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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