Basic Information
VIS ID
TVIS10012385
Fusion event
HBV-LOC110120899 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1764
Orient
-
Integrated sequence
CTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAA| |GGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTG
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
17824864/17671930 (Hg38)
End
17824864/17671930 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC110120899
Nearest miRNA
hsa-mir-1244-3/Upstream/4756012; hsa-let-7i/Downstream/1369;
Nearest TSS
ENST00000382841/Upstream/81938; ENST00000536967/Downstream/418211;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1760330, chr12-CpG: 131/Downstream/1457461
Nearby gene
SKP1P2(-681302) ; MIR3974(+1369) ;
Upstream sequence
TATATATCAAATTTGGTCTTGTTTGTGACATTCTAATATTAACTGATGATTTTTATAGCATTGATTTCATATGGCAATGTTTGTTTTTAATTGATTTAGG
Downstream sequence
TGCTGTGTTCTCAGTAAAACTAACTCATTAGAAAAATGTTCTGAAACCTAGTTGATATCTATTTATTCACTTTTGCAGAGGGTTTTTAGCCAAGACACAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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