Basic Information
VIS ID
TVIS10012386
Fusion event
HBV-LINC01442 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2410
Orient
+
Integrated sequence
GCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAAT| |CGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTAC
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
61497880/60923746 (Hg38)
End
61497880/60923746 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
LINC01442
Nearest miRNA
hsa-mir-1297/Upstream/5749198; hsa-mir-1267/Downstream/276052;
Nearest TSS
ENST00000623511/Upstream/6704; ENST00000455977/Downstream/491776;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/525835, chr13-CpG: 36/Downstream/2887840
Nearby gene
TDRD3(-349867) ; MIR3169(+276052) ;
Upstream sequence
taatcagaggtaggaattagtcaacaactagccaagaggccagtggagctgaagccgagcaagacagggtagagcagaccaaggagaggtcaaagaggag
Downstream sequence
gcccattgtataaaggaggcccattgtataaagctgtcctggccatttcaagcactttttgtttttttttactccaaatgaggtgaaaagccccagaagg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate