Fusion event
HBV-chr17 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|precore/core protein|
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
End
12143967/12240650 (Hg38)
Nearest miRNA
hsa-mir-1253/Upstream/158654; hsa-mir-10226/Downstream/676618;
Nearest cancer related gene
Upstream sequence
ttcattggaattgagccactaggtGATTTGTGATTTCTAGTTCCATCCTTTAGAATGACTTAGACATTTTTGTTTGTTTGTTTGCATGAAAGTTCCAAAT
Downstream sequence
aattcactgataacaccatctgggcctaaagtctttttggaggtaaaattttaaaAACCTTTTAAAAGAATTTTCATGATTTCTTctgggtgtgatggct
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.