Basic Information
VIS ID
TVIS10012397
Fusion event
HBV-chr2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
882
Orient
-
Integrated sequence
GAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGG| |GTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTG
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
164763558/163907048 (Hg38)
End
164763558/163907048 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-128-1/Upstream/3499166; hsa-mir-10b/Downstream/4675895;
Nearest TSS
ENST00000437798/Upstream/171036; ENST00000628960/Downstream/445175;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/170047, chr2-CpG: 87/Downstream/714004
Nearby gene
FIGN(-171045) ; GRB14(+585765) ;
Upstream sequence
acgtgaaagaagccagacacaaaagaccacatatcctatgattccattttaataaaatatccagaataggtgactccatagagaaacaagaatagtggtt
Downstream sequence
tccagagcctgcaggagaaggggaatagggagtgactgctaatggatatagagcttcttttggagggatgaatttttctagaatttgatagtgaggatga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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