VISDB Viral Integration Site DataBase

VIS ID

TVIS10012399

Fusion event

HBV-LPAR3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1754

Orient

-

Integrated sequence

CATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGA| |TTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCA

Chromosome

chr1

Cytoband

p22.3

Reference genome

Start

End

85312028/84846345 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-8485 ; hsa-mir-448 ; hsa-mir-4789-5p ; hsa-mir-4643 ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p

Nearest miRNA

hsa-mir-101-1/Upstream/7786143; hsa-mir-11399/Downstream/287449;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/91690, chr1-CpG: 89/Downstream/46331

Upstream sequence

AACTACGAATCACATTGCTCCAATTAAGGTTAGAAATGCTCTAATTTGTGTTTCCTTGAAAGTTCCAGTCTTATTAGAGAGTCTCAAAACACAATATTGC

Downstream sequence

AGAACTGCATACAATTTTTTATTTTCGTAATGCTATAGTGATAGGCTCCTGTGTCCAATTCAGATTGGTGACATGCTGCTTGAAACTAGTAAACCTTGTC