VISDB Viral Integration Site DataBase

VIS ID

TVIS10012402

Fusion event

HBV-SLC5A8 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1748

Orient

-

Integrated sequence

GTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGG| |AGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCT

Chromosome

chr12

Cytoband

q23.1

Reference genome

Start

End

101552977/101159199 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4777-3p ; hsa-mir-4305 ; hsa-mir-3156-5p ; hsa-mir-640 ; hsa-mir-3151-3p ; hsa-mir-8485 ; hsa-mir-570-3p ; hsa-mir-200b-5p ; hsa-mir-200a-5p

Nearest miRNA

hsa-let-7i/Upstream/969250; hsa-mir-1178/Downstream/2771226;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/441355, chr12-CpG: 62/Downstream/50410

Nearest cancer related gene

SLC5A8(TSG, No orient, 0)

Upstream sequence

ctctagcctggactgaccaaattaggacctctgcaggtaggacccctgaagcctgatttttataaaatttccaagaggatccttatgccctctaaagttt

Downstream sequence

aagaaccactACTTTAGTACAAATACTAGACTTTTAATTATGGGAACCTCTGCTGTTCTGGAGATAGAATCAATTTTAAATGAattcgttcaatgttatt