VISDB Viral Integration Site DataBase

VIS ID

TVIS10012403

Fusion event

HBV-SLC5A8 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1240

Orient

-

Integrated sequence

ACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCG| |TGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAAC

Chromosome

chr12

Cytoband

q23.1

Reference genome

Start

End

101553052/101159274 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4777-3p ; hsa-mir-4305 ; hsa-mir-3156-5p ; hsa-mir-640 ; hsa-mir-3151-3p ; hsa-mir-8485 ; hsa-mir-570-3p ; hsa-mir-200b-5p ; hsa-mir-200a-5p

Nearest miRNA

hsa-let-7i/Upstream/969325; hsa-mir-1178/Downstream/2771151;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/441430, chr12-CpG: 62/Downstream/50335

Nearest cancer related gene

SLC5A8(TSG, No orient, 0)

Upstream sequence

aggatccttatgccctctaaagtttaagaaccactACTTTAGTACAAATACTAGACTTTTAATTATGGGAACCTCTGCTGTTCTGGAGATAGAATCAATT

Downstream sequence

TTAAATGAattcgttcaatgttattgagtacctactgtgtgctggagatgctgctaggtgctagagaaacaaagaaacaaaacaatctctgtgcccacag