VISDB Viral Integration Site DataBase

VIS ID

TVIS10012404

Fusion event

HBV-ARID2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1792

Orient

-

Integrated sequence

CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG

Chromosome

chr12

Cytoband

q12

Reference genome

Start

End

46142518/45748735 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-155-5p ; hsa-mir-424-3p ; hsa-mir-15b-5p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-374a-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4474-3p ; hsa-mir-222-5p ; hsa-mir-4501 ; hsa-mir-545-5p ; hsa-mir-802 ; hsa-mir-203a-3p ; hsa-mir-194-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-127-5p ; hsa-mir-6071 ; hsa-mir-7160-5p ; hsa-mir-8077 ; hsa-mir-4663 ; hsa-mir-873-3p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-3692-5p ; hsa-mir-93-3p ; hsa-mir-4329 ; hsa-mir-6728-3p ; hsa-mir-4499 ; hsa-mir-5584-3p ; hsa-mir-4277

Nearest miRNA

hsa-mir-1244-3/Upstream/3424876; hsa-let-7i/Downstream/1439077;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/18063, chr12-CpG: 115/Downstream/241043

Nearest cancer related gene

ARID2(TSG, No orient, 0)

Upstream sequence

gtttggtagcaaattacccacagtagaacataatttgagtcagtcctcacaaaccctgccactgctttatcaactaaatttatatactgttctaaatcct

Downstream sequence

ttgttgtcatttcagcaatgttcacagcatcttcaccgagaatacattctatctcaataaaccattttctttgctcatccctgagaaggaactcctcatt