C2orf66 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012408
Fusion event
HBV-C2orf66 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1771
Orient
-
Integrated sequence
ACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTT| |GTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGC
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
End
197672790/196808066 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10b/Upstream/7674955; hsa-mir-1244-1/Downstream/9975168;
Upstream sequence
TCTTCCTTAATATGAGATCTCTGTTGTTGCCTTCTGCAATAGTTTCTTTTCAGATTTCCATTAGGAAATGAACACAGAAGATGTGCGAAGTGCTACTTGC
Downstream sequence
TTtgatgcaggacaggcaaatcccaaaactggagcttagcacaggagggttcttggctttgcccagaaaagaatttaagggcaggctggttgtggtaaca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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