Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012412
Fusion event
HBV-IL1RAPL2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1790
Orient
-
Integrated sequence
ACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGC| |ATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGG
Host Sequence
Chromosome
chrX
Cytoband
q22.3
Reference genome
End
104832991/105588998 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7f-2/Upstream/10525772; hsa-mir-105-1/Downstream/1050816;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1021636, chrX-CpG: 62/Downstream/233343
Upstream sequence
AGGGCTCATCCCCTGTACATCAGCTAGCAGGTTGGCAGCAAGACCAATCCCAGGCTGTGGCTGCTGGAGGAACAGGAGAAATCATGGGTTTCTGCCTTGG
Downstream sequence
accagcagtgcataagtgttcttttttctccacaaccttgccaacatctgttaatttttgactttttgataatagccattccaagtggagtgagatgata
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.