Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012422
Fusion event
HBV-FAM149A integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1569
Orient
-
Integrated sequence
GGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATC| |TGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTT
Host Sequence
Chromosome
chr4
Cytoband
q35.1
Reference genome
End
187068825/186147671 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/1209231;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2365, chr4-CpG: 144/Downstream/43114
Upstream sequence
TTAGTCCTTTACCTGTTTATTTTAAAGATGTTTTTGTCCTTTTTCTTAAAGCAGCTGAATCATTGCAAACTTTTATTTTCCCAAACCTTTATGAAGTAAC
Downstream sequence
GTTCAAAACAAATCTATTTGATGTAACTTTTAGTTGTTATTTTATGTCATTAGTATTTGTATGTTTACCTAAAAAGTTACTGAGTCACATGTAAACAAGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.