CDHR3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012430
Fusion event
HBV-CDHR3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1799
Orient
-
Integrated sequence
GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG
Host Sequence
Chromosome
chr7
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
105594673/105954227 (Hg38)
End
105594673/105954227 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
CDHR3
miRNAs that regulate target gene
hsa-mir-331-3p
Nearest miRNA
hsa-mir-10525/Upstream/3482696; hsa-mir-10399/Downstream/8699118;
Nearest TSS
ENST00000635602/Upstream/43188; ENST00000461766/Downstream/9012;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/76710, chr7-CpG: 19/Downstream/55353
Nearby gene
ATXN7L1(-77642) ; CDHR3(+8984) ;
Upstream sequence
tacttgggagactgagacaggagaatcgcttgaacctgggaggtagagattgcagtgagtcaagatcgagccactgcactccagcctgggtgacagagtg
Downstream sequence
agacgtttattgcagcattacttgtaataggaaaaaattgataacaaagcaaacccccatcaatagcagacttgataaatacgtggcacatcaatacaat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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