VISDB Viral Integration Site DataBase

VIS ID

TVIS10012432

Fusion event

HBV-DGKI integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

726

Orient

-

Integrated sequence

TTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTT| |TGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGG

Chromosome

chr7

Cytoband

q33

Reference genome

Start

End

137255781/137571035 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-4786-3p ; hsa-mir-4635 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p

Nearest miRNA

hsa-mir-10525/Upstream/667741; hsa-mir-10399/Downstream/552723;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/406436, chr7-CpG: 117/Downstream/275344

Upstream sequence

tgcacattttctgtccctagtttctcccttttgaccaatgaaatcacctgagacagaggtgGCACTAGAAATCACGTCTTTATTCTAAGTCCAGGACTCT

Downstream sequence

GTTTTTCCTAAGCAACTCTATAATTCATAAAATGTGTAACTTGATAAAGCAGGAGAAAAAGTTAACTAAAGTCCTGTGAATTGAATAAACTCTGTGACTA