Basic Information
VIS ID
TVIS10012436
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
3213
Orient
-
Integrated sequence
CAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG| |
Host Sequence
Chromosome
chr1
Cytoband
q25.3
Reference genome
End
185665193/185696061 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/5257671; hsa-mir-1182/Downstream/7020267;
Nearby gene
GS1-279B7.1(-361022) ; HMCN1(+38490) ;
Upstream sequence
ACGTGGGGTTTACCTTGGTCCAAGAAAAGAAGACAGTTTTCAACTATAACATCCTGTGACTTCATTTTCCAAGTTTCCTCATCACAATATAGAAAAGCTA
Downstream sequence
TATGATGTCCGCTGGGTATACAGCAGTGCTCTGTGTAGCTTAAAGAACATGTAGTTCCAGCATGAAGTTCTGCAAGAGTGGGCCTGGTGTGCTGTGTGTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate