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VISDB
Viral Integration Site DataBase
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TVIS10012461
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012461
Fusion event
HBV-BMPR1A integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
234
Orient
+
Integrated sequence
GATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTC| |ACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATC
Host Sequence
Chromosome
chr10
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
88541300/86781543 (Hg38)
End
88541300/86781543 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
BMPR1A
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-455-3p
;
hsa-mir-656-3p
;
hsa-mir-580-3p
;
hsa-mir-548l
;
hsa-mir-510-3p
;
hsa-mir-431-5p
;
hsa-mir-3140-3p
;
hsa-mir-203a-3p
;
hsa-mir-302f
;
hsa-mir-3616-5p
;
hsa-mir-573
;
hsa-mir-34a-3p
;
hsa-mir-1264
;
hsa-mir-574-5p
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-6867-5p
;
hsa-mir-223-5p
;
hsa-mir-5585-3p
;
hsa-mir-5011-5p
;
hsa-mir-511-3p
;
hsa-mir-1273e
;
hsa-mir-765
;
hsa-mir-766-5p
;
hsa-mir-4459
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-367-3p
;
hsa-mir-363-3p
;
hsa-mir-32-5p
;
hsa-mir-25-3p
;
hsa-mir-4521
;
hsa-mir-34c-3p
;
hsa-mir-1197
;
hsa-mir-499b-3p
;
hsa-mir-499a-3p
;
hsa-mir-8485
;
hsa-mir-6816-3p
;
hsa-mir-8080
;
hsa-mir-139-3p
;
hsa-mir-8055
;
hsa-mir-6739-5p
;
hsa-mir-6733-5p
;
hsa-mir-3153
;
hsa-mir-6770-5p
;
hsa-mir-1253
;
hsa-mir-9500
;
hsa-mir-6822-5p
;
hsa-mir-6750-5p
;
hsa-mir-5584-5p
;
hsa-mir-6783-3p
;
hsa-mir-1343-3p
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-4695-3p
;
hsa-mir-4772-3p
;
hsa-mir-1281
;
hsa-mir-6742-3p
;
hsa-mir-6852-5p
;
hsa-mir-660-3p
;
hsa-mir-4485-5p
;
hsa-mir-6736-3p
;
hsa-mir-6890-3p
;
hsa-mir-6513-3p
;
hsa-mir-8062
;
hsa-mir-4755-5p
;
hsa-mir-5006-3p
;
hsa-mir-6832-3p
;
hsa-mir-623
;
hsa-mir-5692a
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-548n
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-4762-3p
;
hsa-mir-3192-3p
;
hsa-mir-29a-5p
;
hsa-mir-3920
;
hsa-mir-6787-3p
;
hsa-mir-1304-3p
;
hsa-mir-1237-3p
;
hsa-mir-885-3p
;
hsa-mir-1247-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-3689d
;
hsa-mir-377-5p
;
hsa-mir-4279
;
hsa-mir-450b-3p
;
hsa-mir-4713-3p
;
hsa-mir-4722-3p
;
hsa-mir-6086
;
hsa-mir-6134
;
hsa-mir-619-5p
;
hsa-mir-638
;
hsa-mir-6506-5p
;
hsa-mir-6727-3p
;
hsa-mir-6747-3p
;
hsa-mir-6802-3p
;
hsa-mir-6851-5p
;
hsa-mir-6880-5p
;
hsa-mir-769-3p
;
hsa-mir-7847-3p
Nearest miRNA
hsa-mir-1265/Upstream/516755; hsa-mir-107/Downstream/722338;
Nearest TSS
ENST00000439456/Upstream/24893;
ENST00000480152/Downstream/57319;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/24083
,
chr10-CpG: 108/Downstream/161015
Nearest cancer related gene
BMPR1A
(TSG, No orient, 0)
Upstream sequence
tattttcaggtgttgtattgtgatacctccaactttttgctcagggttgctttggttattcgggggcttttgtggttctgtacaaattttaggatttgtt
Downstream sequence
tttccgtgaagaatgtcattggtattttgatagggattgcattggatctgtagattgctttgtgtagtatttctggcactttctcatcttgcctgactga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Sample Information
×
Sample name
807Ca
Sample type
Tumor
Gender
Female
CpG Island Information
×
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