Fusion event
HBV-chr12 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
TATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCC| |TCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCC
End
66451373/66057593 (Hg38)
Nearest miRNA
hsa-let-7i/Upstream/33867; hsa-mir-1178/Downstream/193489;
Nearest cancer related gene
Upstream sequence
aacaaacaaacaaacatgaaaaggcaaacaaacaTGAAAAGGCAAATGATAGAACTGGCCAGTTCCATTTCTAATGGCCTGAGTGGACTCATTCTAGAAt
Downstream sequence
tttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttgagacggagtc
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.