Basic Information
VIS ID
TVIS10012475
Fusion event
HBV-RBM26-AS1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
418
Orient
+
Integrated sequence
TCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGC| |TGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATG
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
79985459/79411324 (Hg38)
End
79985459/79411324 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
RBM26-AS1
Nearest miRNA
hsa-mir-1297/Upstream/1713208; hsa-mir-1267/Downstream/8207341;
Nearest TSS
ENST00000623511/Upstream/4847; ENST00000494647/Downstream/69800;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/4736, chr13-CpG: 75/Downstream/69607
Upstream sequence
aatatgaatcttggtctggcacagtggctcacacctataaccccagcactttgggaggccgaggcaggcggatcacttgaggtcaggagttcaagaccgg
Downstream sequence
cctggccaacatggtgaaaccccatctctactaaaaatacaaaaattagccaggtgtgttggcacacacctgtagtacccagcccagaggctgaggtggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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