VISDB Viral Integration Site DataBase

VIS ID

TVIS10012477

Fusion event

HBV-FLVCR2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

418

Orient

+

Integrated sequence

TCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGC| |TGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATG

Chromosome

chr14

Cytoband

q24.3

Reference genome

Start

End

76055036/75588693 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7c-3p ; hsa-mir-1273h-3p ; hsa-mir-4771 ; hsa-mir-3166 ; hsa-mir-4643 ; hsa-mir-8485

Nearest miRNA

hsa-mir-208a/Upstream/1108489; hsa-mir-1185-1/Downstream/1677525;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/9934, chr14-CpG: 50/Downstream/72472

Upstream sequence

tcagcctccagagtaactgggattacaggcacctgtcaccatgcccagaaaatttttgtatttttaggagagatagggtttcaccatgttggccaggatg

Downstream sequence

gtcttgaactcctgacctcaagtgatccccctgcctcggcctcccaaagtgtttggattacaggcgtgagccactgcacctggccccccaacacatgaac