Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012496
Fusion event
HBV-NBAS integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1640
Orient
+
Integrated sequence
CGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATAT| |TGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGA
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
Start
End
15517696/15377572 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-3125/Upstream/2640128; hsa-mir-10b/Downstream/3970857;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/741887, chr2-CpG: 27/Downstream/183443
Upstream sequence
tacatactcagttaatattacaatagccctatgatataagcctactattatccacattttacaggtgaagaacctgaggccctgatgactggcccaaggt
Downstream sequence
cacatacctgttagctggaaaaaagtggatttgcacatagccatctggccctagaaactgctgtgttcttaacctctacactctgctgCTTCTTGGACAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.