Basic Information
VIS ID
TVIS10012499
Fusion event
HBV-chr2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1816
Orient
-
Integrated sequence
CTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCA| |TGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
End
90374444/90399591 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-1285-2/Upstream/1587137; hsa-mir-10b/Downstream/6398687;
Nearby gene
MIR4436A(-1262476) ; LSP1P4(+1450265) ;
Upstream sequence
actccgttcaatcccattcggtgttccccttcgattgtctttgatgatcattccattcgattcaatttggtgattccattccatgatgattcctttcgat
Downstream sequence
tccattcgatgaggattccattcggttccatttgatgatgattacattcgattccatttgacgatgattccattcgagtccatttgatgattacattcga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate