VISDB Viral Integration Site DataBase

VIS ID

TVIS10012505

Fusion event

HBV-XKR7 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1808

Orient

+

Integrated sequence

TTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCAC| |CAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGAC

Chromosome

chr20

Cytoband

q11.21

Reference genome

Start

End

30564101/31976298 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-874-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-3649 ; hsa-mir-146b-3p ; hsa-mir-6799-3p ; hsa-mir-7976 ; hsa-mir-3173-5p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-6859-3p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-764 ; hsa-mir-660-5p ; hsa-mir-137 ; hsa-mir-367-3p ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-363-3p ; hsa-mir-5186 ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-624-5p ; hsa-mir-590-3p ; hsa-mir-374b-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-6124 ; hsa-mir-1252-5p ; hsa-mir-646 ; hsa-mir-922 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-651-3p ; hsa-mir-3180-5p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-4267 ; hsa-mir-1207-3p

Nearest miRNA

hsa-mir-103a-2/Upstream/369058; hsa-mir-1-1/Downstream/261497;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/7599, chr20-CpG: 32/Downstream/18687

Upstream sequence

gagaagagtggccttccaattcataaggagcaaagctagggtttgaagccatgaggtcaggctcccaaacccacatgtggaaccaccaaactatactgtC

Downstream sequence

TTCTGCTAGTTAAGTGTATTCTTACAAACAATCAATCATGTATTGTTTAGAGAAGCAGAAGAAAAAATATCAGAAAAGTAtttttatttttttttatttt