VISDB Viral Integration Site DataBase

VIS ID

TVIS10012527

Fusion event

HBV-SENP6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

418

Orient

+

Integrated sequence

TCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGC| |TGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATG

Chromosome

chr6

Cytoband

q14.1

Reference genome

Start

End

76418415/75708699 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-640 ; hsa-mir-510-3p ; hsa-mir-488-3p ; hsa-mir-5696 ; hsa-mir-5701 ; hsa-mir-4796-5p ; hsa-mir-1284 ; hsa-mir-4729

Nearest miRNA

hsa-mir-10398/Upstream/280226; hsa-mir-10524/Downstream/2830564;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/105852, chr6-CpG: 104/Downstream/40021

Upstream sequence

cccacacattaataatgggagactttaataccccactgtcaacattagacagatcagtgagacagaaagttaacaaggatacccaggaattgaactcagc

Downstream sequence

gcctggtcaacatggcaaaaccccatctctactaaaaatacaaaaatgccaggcatggtggtatgtacctgtaatcccagctactcagtaggctgaggca