VISDB Viral Integration Site DataBase

VIS ID

TVIS10012538

Fusion event

HBV-SOAT1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2145

Orient

+

Integrated sequence

TTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCT| |AGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAG

Chromosome

chr1

Cytoband

q25.2

Reference genome

Start

End

179303098/179333963 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-1303 ; hsa-mir-500a-3p ; hsa-mir-186-5p ; hsa-mir-4684-5p ; hsa-mir-3675-3p ; hsa-mir-2681-3p ; hsa-mir-6771-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-665 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-122-3p ; hsa-mir-1321 ; hsa-mir-4270 ; hsa-mir-4441 ; hsa-mir-4682 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-6753-5p ; hsa-mir-6754-5p ; hsa-mir-7113-5p ; hsa-mir-8077

Nearest miRNA

hsa-mir-101-1/Upstream/656129; hsa-mir-1182/Downstream/469961;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/39777, chr1-CpG: 47/Downstream/31696

Upstream sequence

CTCATTTTTTGTCAAGTGGTGAAAGCAGCTAGCTGAATAATATTCAGGACTGTCAACCAAATGGGAGGTCAGAAGCTCACCCAGTCGGCTGCAACCATGG

Downstream sequence

CGGAGCCAGAGGGGCTCAAGGGGCCTGTGCTATACCAAGGCTGCAGTTCCTTGCAATGCTCTAGATGACCCTGGGCAGTCTATTCTTGAGCCCCTTCATA