TEAD4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012568
Fusion event
HBV-TEAD4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2568
Orient
-
Integrated sequence
ATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGA| |CATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACC
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
3098245/2989079 (Hg38)
End
3098245/2989079 (Hg38)
Orient
+
Location type
Intronic
Target gene
TEAD4
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-181a-5p ; hsa-mir-512-5p
Nearest miRNA
hsa-mir-3649/Upstream/1328699; hsa-let-7i/Downstream/3974620;
Nearest TSS
ENST00000382841/Upstream/29135; ENST00000544666/Downstream/21965;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/28801, chr12-CpG: 91/Downstream/87766
Upstream sequence
tagatagtgtttctctgagttctgtgagctactatggcaggttaattgatcctaaggagagggttctaggaaccccacctatagctggtgggtcagaagc
Downstream sequence
acaggtaaaacaacccagggcatgggattggcatgggaagtcgggaggcagtcctgtggaaccgagcccccaccctgtgggatctcctggcttcaagcaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate