VISDB Viral Integration Site DataBase

VIS ID

TVIS10012576

Fusion event

HBV-DMXL2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1817

Orient

+

Integrated sequence

TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT

Chromosome

chr15

Cytoband

q21.2

Reference genome

Start

End

51748914/51456717 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-205-5p

Nearest miRNA

hsa-mir-10393/Upstream/142608; hsa-mir-11181/Downstream/820400;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/114596, chr15-CpG: 109/Downstream/165253

Upstream sequence

TCTTCAAGTGCCCCTCCCTGAGGATATTCAGGAGCACCTCCAGATGCTTCAGAGCAGAACATAAGAATGGGACCCCTCCAGCTACAGTGACAAGAATGTT

Downstream sequence

ACTGACATGCTTTCAAGCACTTAGAAGTAGACATGAATTCCCCTTTAACTttgctttaccattttgtatctgtttattcatctgtaaaatgataatggag