VISDB Viral Integration Site DataBase

VIS ID

TVIS10012583

Fusion event

HBV-JPH3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

403

Orient

+

Integrated sequence

GGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCT| |TCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAAC

Chromosome

chr16

Cytoband

q24.2

Reference genome

Start

End

87640760/87607154 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6749-3p ; hsa-mir-202-5p ; hsa-mir-642a-5p ; hsa-mir-6845-3p ; hsa-mir-4469 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-1910-5p ; hsa-mir-455-3p

Nearest miRNA

hsa-mir-12128/Upstream/1688738; hsa-mir-11401/Downstream/227438;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/3476, chr16-CpG: 56/Downstream/7326

Upstream sequence

TGCCCCTGTGCAAAAACACCTCCTGTTCTTTCCTCTCGTTTATATCTCTCGTTCTCTTGTGCGTACAGTGGCCCAGAATTGCAGGTGAATGCCCATGCAC

Downstream sequence

AGACGGGCAAACCCATACACTGCCCAGGACCCCTGGCCCCCTGAGGCCCACCATGCATGCCGGTGCTGCACCGCACAGGTATAGATCTTTCCTTCGGGTG