VISDB Viral Integration Site DataBase

VIS ID

TVIS10012608

Fusion event

HBV-FAM162A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1841

Orient

+

Integrated sequence

TTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAAT| |CATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTG

Chromosome

chr3

Cytoband

q21.1

Reference genome

Start

End

122113274/122394427 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-139-5p ; hsa-mir-6516-5p ; hsa-mir-1273e ; hsa-mir-455-3p ; hsa-mir-139-3p ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-219b-3p ; hsa-mir-6746-5p ; hsa-mir-1247-3p ; hsa-mir-302f

Nearest miRNA

hsa-let-7g/Upstream/1344712; hsa-mir-12124/Downstream/767367;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/10076, chr3-CpG: 29/Downstream/21411

Upstream sequence

catgagatcaactttttaagatcccacacgtgagtgacagaatgtggtatttgtcttttttcacttttctaacctagttatttcacttaacatagcaatc

Downstream sequence

ctccagttactagctgaccactaagataaccagacagacctctgtggccaaacacacaaaggatacaaggagagactatgaacaactctatggcaaaaat