VISDB Viral Integration Site DataBase

VIS ID

TVIS10012612

Fusion event

HBV-CADPS integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1820

Orient

-

Integrated sequence

TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTAT

Chromosome

chr3

Cytoband

p14.2

Reference genome

Start

End

62441818/62456143 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-5096 ; hsa-mir-377-3p ; hsa-mir-4643 ; hsa-mir-8485 ; hsa-mir-8064 ; hsa-mir-335-3p ; hsa-mir-561-3p

Nearest miRNA

hsa-let-7g/Upstream/1838273; hsa-mir-12124/Downstream/4769321;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/77502, chr3-CpG: 127/Downstream/417799

Upstream sequence

tacccagtagtcattcaggagcaggttgttcagtttccatgtagttgagcagttttgagtgaatttcttaatcctgagttctagtttgatttcactgtgg

Downstream sequence

tttcagtttccgcaactgcaaaatggagtggctagaAAGTATcagtacttcccagacttccagcatcaatacaccttcctgattttggctgcaacccatg