Fusion event
HBV-chr3 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|Polymerase|
Integrated sequence
GACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCT| |CGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACA
End
86485076/86435926 (Hg38)
Nearest miRNA
hsa-let-7g/Upstream/1050134; hsa-mir-12124/Downstream/790263;
Nearest cancer related gene
Upstream sequence
attgaactcatctctgcaccaagcggacctaatagacatctacagaactctccaccccaaatcaacagaatatacatttttttcagcaccacaccacacc
Downstream sequence
CTTTTTTTCTAGTTTCATGCAGAAAGATAATTCGGCTATTGAAGAAACATAATGTCTAAAACCAAACAGATAGAATACCAACTATTTTTGATACATTGAT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.