VISDB Viral Integration Site DataBase

VIS ID

TVIS10012629

Fusion event

HBV-GABRB2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

481

Orient

-

Integrated sequence

TGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTC| |TAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACC

Chromosome

chr5

Cytoband

q34

Reference genome

Start

End

160868054/161441048 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-5197-5p ; hsa-mir-335-3p ; hsa-mir-374a-3p ; hsa-mir-6515-5p ; hsa-mir-4443 ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-382-3p ; hsa-mir-8081 ; hsa-mir-6818-5p ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-4758-5p ; hsa-mir-1238-5p ; hsa-mir-943 ; hsa-mir-6867-5p ; hsa-mir-6820-3p ; hsa-mir-3164 ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-3659 ; hsa-mir-574-5p ; hsa-mir-892a ; hsa-mir-511-3p

Nearest miRNA

hsa-mir-10397/Upstream/955598; hsa-mir-103a-1/Downstream/6724797;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/1018942, chr5-CpG: 68/Downstream/106638

Upstream sequence

catgtagttgagcggttttgggtgagtttcttaatcctgagttctagtttgattgaactgtggtctgagagacagtttgttataatttccgttcttttac

Downstream sequence

ctgggcaaagatttcgtgagcagtacctgcaagcacaggcaaccaaagcaaaaatagacaaatgggatcacatcaagttaaaaagcatctgcacagtaaa