Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012632
Fusion event
HBV-WDR27 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2871
Orient
+
Integrated sequence
GTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCA| |GCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTG
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
End
169921460/169521365 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/2523453; hsa-mir-4644/Downstream/809396;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/68780, chr6-CpG: 65/Downstream/55757
Upstream sequence
GCAGAACCAGAAGTTGCTGGGGGCTGCAGAGCATTTTCTTTCTTTCTTACTGGCAGAATCCTACTCAGGAAAGGGGAGAAACTTTCAGAAAAGGGAGTGA
Downstream sequence
ggagacctgtctataagaaatgctaaagaaaggtcttcaatctaaagaaaaaaataaaaaacacttaacatgcaagaagaaagcatttcaaggtattaaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.