Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012633
Fusion event
HBV-WDR27 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2151
Orient
+
Integrated sequence
TCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGAC| |CTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAG
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
End
169921468/169521373 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/2523461; hsa-mir-4644/Downstream/809388;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/68788, chr6-CpG: 65/Downstream/55749
Upstream sequence
ttaaggttatctcacttgttccttgaaaatcactgttatcctgttcttaaggtgcccagatttcatattgttcaaacacacatgctttacgaacaatttg
Downstream sequence
gtctataagaaatgctaaagaaaggtcttcaatctaaagaaaaaaataaaaaacacttaacatgcaagaagaaagcatttcaaggtattaaacccactga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.