Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012641
Fusion event
HBV-ADAM32 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1761
Orient
+
Integrated sequence
GGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTT| |AAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTA
Host Sequence
Chromosome
chr8
Cytoband
p11.22
Reference genome
Start
End
39092506/39234987 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-124-1/Upstream/9277639; hsa-mir-10400/Downstream/2036061;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/127083, chr8-CpG: 30/Downstream/287719
Upstream sequence
ttccggttcaagcgattctcctgcctcagcctcctgagtaactgggattacaggcacccgccaccacgcccaactaatttctgtatttttcttagtagaa
Downstream sequence
tctctccttccccccgcccctctctgtctgactcttcattcctgtgtcctgtgacctggggatggaggactgccctcctggtacaatgtgctctccctgc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.