VISDB Viral Integration Site DataBase

VIS ID

TVIS10012643

Fusion event

HBV-SLCO5A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

536

Orient

-

Integrated sequence

TGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTAC| |TGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAA

Chromosome

chr8

Cytoband

q13.3

Reference genome

Start

End

70602386/69690151 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-4511 ; hsa-mir-548b-3p ; hsa-mir-548s ; hsa-mir-6873-3p ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6892-3p ; hsa-mir-6849-3p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-4684-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-1276 ; hsa-mir-320e ; hsa-mir-519a-3p ; hsa-mir-519b-3p ; hsa-mir-519c-3p ; hsa-mir-6128 ; hsa-mir-767-5p

Nearest miRNA

hsa-mir-124-1/Upstream/5310894; hsa-mir-10400/Downstream/4858392;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/1358583, chr8-CpG: 224/Downstream/141712

Upstream sequence

ttgattttgagtgattttcttagtattgatttttgtttttattttgctgtagtctgagaatgtggttggttgtgtgagtatatgtttaatttgctgggga

Downstream sequence

ttccgccaagcccgttcccttggctgtggtttcgctggatagtaggtagggacagtgggaatctcgttcatccattcatgcgcgtcactaattagatgac